BIEMANS RALPH,DENOEL PHILIPPE,FERON CHRISTIANE,GORAJ KARINE,POOLMAN JAN,WEYNANTS VINCENT
申请号：
PL39949203
公开号：
PL399492A1
申请日:
2003.07.31
申请国别(地区):
PL
年份:
2012
代理人:
摘要：
The present invention relates to immunogenic compositions and vaccines for the treatment and prevention of Neisserial disease. Immunogenic compositions of the invention contain combinations of antigens selected from at least two different classes of antigens including adhesins, autotransporter proteins, toxins, iron acquisitions proteins and membrane-associated protein (preferably integral outer membrane protein)s. Such combinations of antigens are able to target the immune response against different aspects of the neisserial life cycle, resulting in a more effective immune response.
