PURPOSE: A GABA_A receptor ligand composition containing linalool is provided to treat depression, anxiety, mania, and post-traumatic stress disorder. CONSTITUTION: A GABA_A receptor ligand composition contains linalool as an active ingredient. A composition for preventing or treating central nervous system disorder contains linalool. The composition is a functional food composition or pharmaceutical composition. The content of linalool is 0.001-95 wt% based on the total composition. The composition further contains pharmaceutically acceptable carrier. The carrier includes carbohydrate compounds, calcium phosphate, alginate, gelatin, micro-crystalline cellulose, polyvinyl pyrrolidone, cellulose, water, syrup, alcohol, arabia rubber, polyethylene glycol, methyl cellulose, methyhydroxy benzoate, or mineral oil.본 발명은 리나룰을 유효성분으로 포함하는 GABAA수용체 리간드 조성물에 관한 것으로, 더욱 구체적으로는 우울증, 조증, 불안 장애, 알츠하이머병 또는 파킨슨 병으로 인한 치매, 또는 수면 장애 등의 중추신경계 장애를 예방, 치료, 또는 개선하기 위한 조성물에 관한 것이다.
