Frank Bröcker;Adrian Funke;Erich Brendel;Thomas Volkmer;Andreas Ohm;Dennis Kvesic;Alexander Kuhl
发明人:
Alexander Kuhl,Erich Brendel,Frank Bröcker,Adrian Funke,Andreas Ohm,Dennis Kvesic,Thomas Volkmer
申请号:
US13130294
公开号:
US09993432B2
申请日:
2009.11.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a pharmaceutical dosage form comprising an active ingredient combination of nifedipine or nisoldipine and at least one angiotensin II antagonist and/or at least one diuretic, characterized in that nifedipine or nisoldipine is released in the body in a controlled (modified) manner and the angiotensin II antagonist and/or the diuretic is released rapidly (immediate release (IR)), and also to processes for their preparation, to their use as medicaments and to their use for the prophylaxis, secondary prophylaxis or treatment of disorders.