SIN, NY,LIU, ZHENG,SWIDORSKI, JACOB,SIT, SING-YUEN,CHEN, JIE,CHEN, YAN,MEANWELL, NICHOLAS A.,REGUEIRO-REN, ALICIA
申请号:
CA2872891
公开号:
CA2872891C
申请日:
2013.05.03
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 bicyclic amines of triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III:These compounds are useful for the treatment of HIV and AIDS.