Anti CD84 antibodies, compositions comprising same and uses thereof

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专利权人:

Yeda Research and Development Co. Ltd.

发明人:

Idit Shachar,Inbal Binsky,Ayelet Marom

申请号：

US15116276

公开号：

US10066014B2

申请日:

2015.02.05

申请国别(地区):

US

年份:

2018

代理人:

摘要：

An isolated antibody comprising an antigen recognition domain which specifically binds CD84 and(i) down regulates the anti-apoptotic activity of stromal cells on chronic lymphocytic leukemia (CLL) cells； and/or(ii) induces mobilization of CLL cells from the bone marrow.Also provided are antibodies comprising antigen recognition domains comprising complementarity determining regions as indicated and uses thereof.

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