Life Science Institute, Inc.;Gifu University;Tohoku University
发明人:
YOSHIDA, MASANORI,MINATOGUCHI, SHINYA,DEZAWA, MARI
申请号：
PL13879518
公开号：
PL2886123T3
申请日:
2013.08.15
申请国别(地区):
PL
年份:
2020
代理人:
摘要：
An object of the present invention is to provide a novel medical application for use in regenerative medicine that uses pluripotent stem cells (Muse cells). The present invention provides a cell preparation for treating myocardial infarction, and particularly serious massive myocardial infarction and heart failure associated therewith, that contains pluripotent stem cells positive for SSEA-3 isolated from biological mesenchymal tissue or cultured mesenchymal cells. The cell preparation of the present invention is based on a cardiac tissue regeneration mechanism by which Muse cells are made to selectively accumulate in damaged myocardial tissue and differentiate into cardiac muscle in that tissue as a result of intravenous administration of Muse cells to a subject presenting with the aforementioned disorders.
