The invention relates to apparatus for collecting a sample of exfoliated cells from a colorectal mucosal surface of a subject. [SOLUTION] colorectal insertion member having an internal cavity can be closed and (34) (3) (2), the proximal end inserted into the distal end (1), the cell sampling device the outer surface, (5 It is provided with a flexible membrane having an inner surface and) In use, the upward pressure of the first to bring at least an internal cavity, the membrane is out of the distal end of the insertion member the membrane By decreasing the pressure to a second lead to the internal cavity and is contacted with the colorectal mucosal surface, to return to the interior cavity of the insertion member by Uchiten the film is sealed to insert the distal end of the insertion member and is held in the internal cavity and mounted manner. In addition, a method for sampling the colorectal cells using the device is described. [Selection Figure Figure 2【課題】本発明は、被検者の結腸直腸粘膜表面から剥脱細胞の試料を収集するための装置に関する。【解決手段】この装置は、挿入遠位端部(2)、近位端部(34)および閉鎖可能な内部空洞(3)を有する結腸直腸挿入部材(1)と、細胞試料採取外面(5)および内面を有する可撓性の膜とを備えており、前記膜は、使用にあたり、内部空洞を少なくとも第1の上昇圧力までもたらすことにより、膜を前記挿入部材の遠位端部から出して結腸直腸粘膜表面と接触させ、そして内部空洞を第2の減少圧力までもたらすことにより、膜を内転させて前記挿入部材の内部空洞へ戻すように、前記挿入部材の挿入遠位端部に密封的に取付けられ、そして内部空洞に保持されている。また、前記装置を使用して結腸直腸細胞を試料採取する方法が説明される。【選択図】 図2
