Aby J. Mathew;Michael Rice;Ian B. Nicoud;Dominic M. Clarke
发明人:
Dominic M. Clarke,Ian B. Nicoud,Aby J. Mathew,Michael Rice
申请号:
US13265959
公开号:
US09125397B2
申请日:
2010.04.29
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided are apparatuses for cryopreserving cells which include a vessel comprising a biocompatible substrate, wherein the vessel further comprises an interior and an exterior, and a mechanical ice nucleating device disposed in or on the vessel interior for initiating ice crystal formation. Also provided are kits comprising one or more apparatuses for cryopreserving cells and a biopreservation medium. Further provided are compositions comprising a vessel for holding cells, a mechanical ice nucleating device, a biopreservation medium, and cells disposed in the vessel. The apparatuses, kits, and compositions of the invention can optionally include an insulating material which is disposed on all or a portion of the vessel.