The present invention provides a kind of continuous intelligent preparation method of liquid cooling drop pill, comprises the steps:1)Feeding, various materials is weighed respectively, is conveyed;2)Material, to step 1)The material of conveying obtains mixed material, effective ingredient RSD≤5% in the mixed material by progressive solution, mixing;3)Homogenizing, to step 2)The mixed material for obtaining carries out pressurizeing, heats up, and obtains the homogenous mass of effective ingredient RSD≤5%;4)Dripping, by step 3)After the homogenous mass for obtaining carries out vibration dripping, drop pill is obtained, drop pill input coolant is conveyed after being cooled down;5)Removing oil, removes step 4 by inclining centrifugation)The coolant on the drop pill surface of conveying.Not only shorten whole preparation process elapsed time, it is ensured that drop pill product has more stability and uniformity, and is contaminated by drop pill rationally to pill deoiling, that is, is prevented using ultracentrifugal mode, improves the cyclic utilization rate of coolant again.