BIOMARKER-TARGETING CONTRAST AGENTS AND THEIR USE IN MAGNETIC RESONANCE IMAGING FOR DETECTION OF ATHEROSCLEROTIC PLAQUE

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专利权人:

发明人:

Zhiguo Zhou,Robert P. Lenk,Christopher L. Kepley

申请号：

US14007649

公开号：

US20140161733A1

申请日:

2012.03.29

申请国别(地区):

US

年份:

2014

代理人:

摘要：

A composition comprising: a liposome having a bilayer structure, a gadofullerene having a high relaxivity, and an amphiphilic receptor ligand. In the composition, the gadofullerene is embedded in the bilayer structure of the liposome. In addition, a method for detecting atherosclerotic plaque in an animal using the composition is described.

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