A physiological sensor includes a flexible substrate, a plurality of sensing module and a processing module. The sensing modules are disposed on the sensor modules and configured to produce sensing signal. The processing module is connected to the sensing module and configured to receive the sensing signal.一種生理感測裝置,包括一軟性基板、多個感測模組及一處理模組。多個感測模組設置於該軟性基板上,適於產生一感測訊號。處理模組連接至該感測模組,適於接收該感測訊號。