A heat transfer composition comprises trans-1,3,3,3-tetrafluoropropene (R-1234ze(E)), difluoromethane (R-32) and 1,1,1,2-tetrafluoroe.thane. (R-134a). The composition preferably has a low GWP and may further comprise a lubricant, a stabiliser or a flame retardant. The composition may be a refrigerant, a blowing agent, a foam or a sprayable composition. The composition may be used in a heat transfer device e.g. automotive air conditioning systems, chiller refrigeration systems. Also shown are methods of cooling, heating, extraction and cleaning using the composition.
