An electronic pill box having a housing with a base and grid and into which a blister pack is selectively engaged. The blister pack includes a plurality of vials prefilled with medication and sealed with a cover imprinted with pertinent information. Each vial is received in a chamber in the base having an LED and a sensor for determining whether medication has been removed therefrom. The LED and sensor are operatively engaged with a microprocessor including programming for dispensing medication from the pill box. An alert is issued if medication is not removed from an illuminated vial after a predetermined time interval. When all medication has been dispensed therefrom, the blister pack is replaced with another prefilled blister pack A card with patient information thereon may be provided on the prefilled blister pack and is detached and stored in the housing prior to loading the blister pack therein.