JUO, SUH HANG,卓夙航,卓夙航,CHEN, KU CHUNG,陈顾中,陳顧中,HSIEH, I CHUNG,谢易仲,謝易仲,HU, CHING YU,胡静育,胡靜育
申请号：
TW100111567
公开号：
TWI421084B
申请日:
2011.04.01
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
A new use of microRNA let-7g includes, used as an inhibitor for reducing the expression of lectin-like oxidized-low-density lipoprotein receptor-1 (LOX-1), furthermore to put to use in pharmaceutics as an active substance of medication for atherosclerosis, and also used as a biomarker for detecting the development of atherosclerosis, for the sake of improving clinical detective detective techniques, as well as the quality of therapy for atherosclerosis.一種微小RNA let-7g的新用途,係以微小RNA let-7g作為抑制氧化低密度脂蛋白受體(LOX-1)表現的抑制劑,進一步將該微小RNA let-7g應用於製備用以治療動脈硬化症之藥物化合物,或者係檢測動脈硬化症之生物標記,以提升動脈硬化症在臨床檢測及治療之技術及品質。
