Mukund Mehrotra;Brian Kane;Yonghong Song;Shawn M. Bauer;Zhaozhong J. Jia;Qing Xu;Anjali Pandey;Jack W. Rose;Wolin Huang
发明人:
Shawn M. Bauer,Yonghong Song,Qing Xu,Jack W. Rose,Zhaozhong J. Jia,Brian Kane,Wolin Huang,Anjali Pandey,Mukund Mehrotra
申请号：
US13286984
公开号：
US20120108566A1
申请日:
2011.11.01
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
