An invention relates to a method for deleting DNA region in a plant comprising plant transforming with nucleic acid molecule, wherein the nucleic acid molecule encodes one or more “zinc finger” nuclease(s) (ZFNs) operably linked to one or more tissue specific promoter(s); transgenic plant, and isolated nucleic acid participating in transgenic plant production method; reduction method for desired gene transfer to other plant comprising plant crossing with regenerate plant from plant cell or tissue, as well.