SPANGENBERG, GERMAN,SAWBRIDGE, TIMOTHY IVOR,ONG, ENG KOK,EMMERLING, MICHAEL
申请号:
NZ58139302
公开号:
NZ581393A
申请日:
2002.10.04
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a substantially purified or isolated nucleic acid or nucleic acid fragment encoding F3H, or complementary or antisense to a sequence encoding F3H, said nucleic acid or nucleic acid sequence including a nucleotide sequence selected from the group consisting of (a) sequences shown in Figure 73 hereto (Sequence ID No: 202) (b) complements of the sequences recited in (a) (c) sequences antisense to the sequences recited in (a) and (b) and (d) functionally active fragments and variants of the sequences recited in (a), (b) or (c), wherein said functionally active fragment or variant has a sequence having at least 80% identity to the sequence upon which the fragment or variant is based and has a size of at least 20 nucleotides. Further disclosed is a substantially purified or isolated F3H polypeptide, wherein said polypeptide includes an amino acid sequence selected from the group consisting of (a) sequences shown in Figure 74 hereto (Sequence ID No: 203) and (b) functionally active fragments and variants of the sequences shown in (a), wherein said functionally active fragment or variant has a sequence having at least 90% identity to a sequence recited in (a).