PROBLEM TO BE SOLVED: To provide a GLP-1 secretion promoter that promotes secretion of GLP-1, and a diabetes preventive or improver, an obesity preventive or improver, an anorectic agent, a glucagon secretion inhibitor, and a gastric emptying retardant which utilize effects of the GLP-1 secretion promoter or are used as means for administering the promoter.SOLUTION: Provided are a GLP-1 secretion promoter, a diabetes preventive or improver, an obesity preventive or improver, an anorectic agent, a glucagon secretion inhibitor, and a gastric emptying retardant which have an antagonist of a cysteinyl leukotriene-1 receptor as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】GLP-1の分泌を促進するGLP-1分泌促進剤、並びに、GLP-1分泌促進剤の効能を生かし、またその投与の手段としての、糖尿病予防又は改善剤、肥満予防又は改善剤、食欲抑制剤、グルカゴン分泌抑制剤、及び胃排泄遅延剤を提供する。【解決手段】システイニルロイコトリエン-1受容体のアンタゴニストを有効成分とする、GLP-1分泌促進剤、糖尿病予防又は改善剤、肥満予防又は改善剤、食欲抑制剤、グルカゴン分泌抑制剤、及び胃排泄遅延剤。【選択図】なし
