Antioxidant stabilized pharmaceutical formulations comprising antineoplastic compounds

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专利权人:

发明人:

Mahmoud S. AlSwisi,Mahmoud A. A. Ghannam

申请号：

US14612660

公开号：

US09211336B2

申请日:

2015.02.03

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to stabilized pharmaceutical formulations prepared from solutions comprising an antineoplastic compound having a cyclic or non-cyclic hydrazine, triazine, or tetrazine group, or a pharmaceutically acceptable salt thereof, and a stabilizer, wherein the stabilizer is an antioxidant and/or more susceptible to nucleophilic attack than the antineoplastic compound.

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