The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and/or a SGLT-2 inhibitor drug, and metformin XR, processes for the preparation thereof, and their use to treat certain diseases.本發明係關於包含DPP-4抑制劑藥物及/或SGLT-2抑制劑藥物與二甲雙胍(metformin)XR之固定劑量組合的醫藥組合物、其製備方法及其治療某些疾病之用途。