processo de preparação de compósitos em base de biocerámicas e polìmeros biodegradáveis, contendo antibióticos e angiotensina (1-7), encapsulados ou não, micro ou nanoparticulados, para restituição tecidual de produtos derivados
André Luiz Parato,Maria Esperanza Cortés Segura,Michele Fabiane de Oliveira,Miriam Tereza Paz Lopes,Regina Maria de Marco Turchetti Maia,Robson Augusto Souza dos Santos,Rubén Dario Sinisterra Millán
申请号：
BRPI0602372
公开号：
BRPI0602372B1
申请日:
2006.05.18
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
Preparation process of composite on the basis of bioceramics and biodegradable polymers, containing antibiotics and angiotensin (1 - 7), encapsulated or not, or to refund nanoparticulados micro tissue and derived products, the present invention is characterized by preparing with Deposits on the basis of bioceramics containing calcium salts such as Ca (PO 4 ~ 5 ~ ~ ~) ~ 3 ~ Oh, CaCO ~ 3 ~ if ~ 4 ~ if ~ 2 ~,Ca ~ 3 ~ (PO ~ 4 ~), caosio ~ 2 ~ (~ 3 ~) ~ 2 ~ Ca ~ 10 ~ (PO ~ 4 ~) ~ 6 ~ (OH) ~ 2 ~, as patent br pi9104220 - 8, (2000), natural and \/ or synthetic biodegradable polymers. Containing antibiotics and angiotensin (1 - 7), encapsulated or not, micro or nanoparticulados, in the form of suspensions, cosmetics, imp Lantes and uses of these compositions in the process of restitution tissue.This technology is related to a method for producing composites, containing antibiotics and angiotensin (1 - 7), which can be used as implants in human and veterinary medicinal products, in fact, antibiotic and osteoconductor. Another feature of the invention is the use of tetracyclines in composites, in concentrations that may vary from 0.0.001% to 5%, in effect, anti-inflammatory, showing a better biocompatibility compared with the material found in the state of the art.The composites of polymer properties biocer\u00e2mica: here claimed are induction of dentin bridge formation of reparative dentin, compact and a matrix with favorable geometry for the mineral deposition with superior characteristics to the materials is presented by In the state of the art.This material induces a tissue repair more effective and causes a histological response compatible with the normal tissue regeneration process.Processo de preparação de compósitos em base de biocerâmicas e polímeros biodegradáveis, contendo antibióticos e angiotensina (1-7), encapsulados ou não, micro ou nanoparticulados, para restituição tecidual e produtos derivados A presente invenção caracteriza-se pela preparação de compósitos
