Access to key diagnostic medical devices requires pre-approval by a screening physician. A computer-implemented system and method for mediating patient-initiated physiological monitoring and ensuring appropriate follow up, bypassing the need for a screening physician, are provided. A request for a medical monitoring device from a patient at a point of prescriptive medicine dispensing is entered. The patient is enrolled in a medical service network that includes healthcare providers and medical services, and one or more on-call prescribing physicians. The patient is interfaced in real time with one of the prescribing physicians. Upon physician approval, the monitoring device is dispensed to the patient at the point of dispensing. Following monitoring, data from the monitoring device is retrieved for the medical service network. The retrieved data is evaluated for medical concerns. Based on findings from the evaluation made, the patient is referred for medical care through the healthcare providers and medical services.