Cell penetrating peptides for intracellular delivery of molecules

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专利权人:

Gilles Divita

发明人:

Gilles Divita,Frédéric Heitz,May Catherine Morris,Gudrun Aldrian-Herrada

申请号：

US12096378

公开号：

US08242081B2

申请日:

2006.12.05

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9RALX9RX1LX2RSLX9X3X4X5X6X7X8 (SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.

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