An inflatable splint can include a sleeve shaped to conform to a specific human body part and a plurality of inflatable chambers disposed on the sleeve. The sleeve, in cooperation with the plurality of chambers in an inflated condition, can be contoured to maintain the specific human body part in a desired position. A method of using an inflatable splint includes admitting a body part into a sleeve of the inflatable splint and positioning the sleeve around the body part One or more of the plurality of air chambers are selectively inflated such that the flexible sleeve in cooperation with the plurality of chambers in inflated condition is contoured and positioned to maintain the specific human body part in a desired position.