National Research Council of Canada;Zymeworks Inc.
发明人:
Anders Ohrn,Adam Louis Corper,Gordon Yiu Kon Ng,Antonios Samiotakis,Yang-Chieh Chou,Jason Baardsnes,Maureen O'Connor-McCourt,Maureen OConnor-McCourt
申请号：
US14432153
公开号：
US09771573B2
申请日:
2013.10.03
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided is a method of quantitatively determining the ability of individual IgG heavy chains to selectively pair with a particular IgG light chain when the heavy chains and two unique light chains are co-expressed. The method provides results with reasonable throughput and is robust and accurate. The co-expressed heavy and light chains do not need to be isolated and purified which enables more efficient screening.
