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More palatable, bioequivalent pharmaceutical composition of carprofen
专利权人:
Jugal K. Taneja
发明人:
Jugal K. Taneja
申请号:
US14329970
公开号:
US09155704B1
申请日:
2014.07.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a more palatable pharmaceutical composition comprising carprofen and at least one flavoring agent, and more particularly pertains to a more palatable and more voluntarily consumed pharmaceutically active dosage of carprofen, made available in the form of an orally administered tablet that is easy to swallow, with the same dissolution profile and bioequivalence of less palatable carprofen compositions, such as those compositions without a flavoring agent, and used for the indication of relieving clinical symptoms of pain and inflammation associated with osteoarthritis and postoperative surgery in mammals, by reduced prostaglandin production via inhibition of cyclooxygenase-2. Also included are analytical methods for in vitro dissolution testing of this unique composition to demonstrate bioequivalence to less palatable non-flavored and chewable compositions.
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