Aaron Anderson;Mark Wolfenden;Jurgen G. Schmidt;Jennifer Foster Harris
发明人:
Jurgen G. Schmidt,Mark Wolfenden,Aaron Anderson,Jennifer Foster Harris
申请号:
US13294966
公开号:
US20120121511A1
申请日:
2011.11.11
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A compound, or a pharmaceutically acceptable salt, ester, hydrate or solvate thereof, comprising formula I:A-Bwherein A comprises a carbohydrate that is a neuraminidase or galactosidase substrate;B comprises an odorant moiety;B is covalently bonded to an anomeric carbon of A; andA is enzymatically cleavable from B at the covalent bond site between A and B. Also disclosed are methods for detecting a pathogen with neuraminidase activity or galactosidase activity that include contacting the compound with a sample that may include the pathogen.