Benjamin Daelken,Christoph Uherek,Kenneth Anderson,Teru Hideshima,Christoph Bruecher,Frank Osterroth,Silke Aigner,Matthias Germer
申请号:
US12342815
公开号:
US09446146B2
申请日:
2008.12.23
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed are immunoconjugates having specificity for CD138 that diminish adhesion of CD138 expressing tumor cells to stroma cells and methods of using the same. This diminished adhesion renders the tumor cells not only susceptible to the immunoconjugate, but also to other agents, in particular cytotoxic agents.