The present invention relates to novel pharmaceutical compositions in which the active agent is a topoisomerase I inhibitor, in particular a camptothecin derivative, that is useful for the treatment and prevention of proliferative diseases including cancer.本發明係關於用於治療且預防包括癌症之增生性疾病之新穎醫藥組合物,其中活性藥劑為拓撲異構酶I抑制劑,特別是喜樹鹼衍生物。