Agenus Inc.;Memorial Sloan-Kettering Cancer Center;Ludwig Institute for Cancer Research Ltd
发明人:
申请号:
EP16871651.2
公开号:
EP3383914A4
申请日:
2016.12.02
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present disclosure provides antibodies that specifically bind to human OX40 receptor (OX40) and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human OX40 and modulate OX40 activity, e.g., reduce, deactivate, or inhibit OX40 activity. The present disclosure also provides methods for autoimmune or inflammatory diseases or disorders, by administering an antibody that specifically binds to human OX40 and modulates OX40 activity, e.g., reduces, deactivates, or inhibits OX40 activity.