Provided herein are pharmaceutical compositions that are useful for the treatment of hypertension comprising an angiotensin II receptor blocker, a diuretic, a calcium channel blocker, and a beta-blocker, wherein the dose of each component is below the lowest dose approved for the treatment of hypertension for the component.本文提供可用於治療高血壓之醫藥組合物,其包含血管收縮肽II受體阻斷劑、利尿劑、鈣通道阻斷劑及β-阻斷劑,其中各組分之劑量低於該組分批准用於治療高血壓之最低劑量。