A method of non-invasive, continuous, real-time measurement of blood pressure includes applying a wearable blood-pressure monitoring device to a bodily region of a wearer. The wearable blood-pressure monitoring device includes a plurality of pulse sensors or a sensor offering a plurality of observations. The wearable blood-pressure monitoring device is calibrated such that a subset of the plurality of pulse sensors or observations are selected. The selected subset of the plurality of pulse sensors measure a pulse wave velocity and other important physiological parameters of the wearer. The measured pulse wave velocity and other important physiological parameters are converted to a blood pressure of the wearer.