PURPOSE: A hedera helix leaf extract or a compound separated from the same are provided to utilize as a medicinal composition for prevention and treatment of an infectious diseas by an influenza virus or a health functional food by checking a high survival rate when taken together with an antivirus agent. CONSTITUTION: A medicinal composition for prevention and treatment of an infectious disease caused by an influenza virus contains a Hedera helix leaf extract or hederacoside C separated from the same as an active ingredient. The Hedera helix leaft extract is a crude extract, a polar solvent soluble extract, and a non-polar solvent soluble extract. The medicinal moposition for prevention and treatment of an infectious disease contains the combination of the Hedera helix leaf extract or hederacoside C and an anti-influenza agent. The anti-influenza agent is selected from Oseltamivir (Tamiflu), Zanamivir (Relenza), Peramivir, Amantadine (Symmetrel), Rimantadine, Rivaririn, or Taribavirin. [Reference numerals] (AA) Survival rate； (BB) Medicine injection； (CC) Time (day) after infection； (DD) Extract of Ivy leaf본 발명은 아이비엽 추출물 및 이로부터 분리된 화합물을 유효성분으로 함유하는 조성물에 관한 것으로, 상세하게는 아이비엽 추출물 및 이로부터 분리된 화합물은 인플루엔자 바이러스 감염에 대한 치료 효과를 실험한 결과, 유의적인 치료효과를 나타냈고, 특히 기존 항인플루엔자제와의 병용투여시 강력한 인플루엔자 감염 치료효과을 나타냄을 확인함으로써, 상기 조성물을 인플루엔자 바이러스에 의한 감염증의 예방 및 치료용 약학조성물 또는 건강기능식품으로 유용하다.
