A pharmaceutical composition comprising 2-hydroxybenzoic acid derivative or its pharmaceutically acceptable salt, wherein the 2-hydroxybenzoic acid derivative is any one selected from the group consisting of 2-hydroxy-5-phenethylamino-benzoic acid, 2-hydroxy acid -5- [2- (4-trifluoromethyl-phenyl) -ethylamino] -benzoic acid, 2- hydroxy-5 - [2- (2-nitro-phenyl) -ethylamino] -benzoic acid, 5- [2 5 - ( 3,4-Difluoro-phenyl) -ethylamino] -2-hydroxy-benzoic acid, 5- [2- (3,4-dichloro-phenyl) -ethylamino] -2-hydroxy-benzoic acid, 5- [2- ( 4-fluoro-2-trifluoromethyl-phenyl) -ethylamino] -2-hydroxybenzoic acid, 5- [2- (2-fluoro-4-trifluoromethyl-phenyl) -ethylamino] -2-hydroxy-benzoic acid, 2-hydroxy- 5- [2- (4-Methoxy-phenyl) -ethylamino] -benzoic acid, 2-hydroxy-5- (2-o-tolyl-ethylamino) -benzoic acid, 2-hydroxy-5- (3-phenyl-propylamino) ) -benzoic acid, 5- [3- (4-fluoro-phenyl) -propylamino] -2-hydroxy-benzoic acid, 5- [3- (3,4-dichloro-phenyl) -propylamino] -2-hydroxy10 benzoic acid , 2-hydroxy-5- (3-p- tolyl-propylamino) -benzoic acid and 2-acetoxy-5- [2- (4-trifluoromethyl-phenyl) -ethylamino] -benzoic acid, for use in the treatment or prevention of inflammatory disease, wherein the inflammatory disease is any selected from the group consisting of gastritis, colitis, pancreatitis, arthritis, inflammation and diabetic pain, arteriosclerosis, nephritis, hepatitis, inflammatory bowel disease, gastric ulcer and hyperalgesia associated with arthritis or rheumatoid arthritis.Una composición farmacéutica que comprende derivado del ácido 2-hidroxibenzoico o su sal farmacéuticamente aceptable, en donde el derivado del ácido 2-hidroxibenzoico es uno cualquiera seleccionado del grupo que consiste en ácido 2-hidroxi-5-fenetilamino-benzoico, ácido 2-hidroxi-5-[2-(4-trifluorometil-fenil)-etilamino]-benzoico, ácido 2- hidroxi-5 -[2-(2-nitro-fenil)-etilamino]-benzoico, ácido 5-[2 5 -(3,4-difluoro-fenil)-etilamino]-2-hidroxi-benzoico, ácido 5-[2- (3,4-dicloro-fenil)-etilamino]-2-hidrox
