A protection device (1) with improved functionality, particularly for syringes or the like, comprising a supporting body (2) which is provided with a through hole (3) for the insertion of the covering cap (4) of a needle (5) of a syringe (6) or the like, the peculiarity of which consisting in that the supporting body (2) is provided with at least one flat face (7), being arranged on the opposite side with respect to a face (9) for the insertion of the covering cap (4) in the hole (3), for the resting contact of the supporting body (2) on a resting surface (8) or the like, the face (9) lying opposite the flat face (7) being provided with a raised perimetric containment rim (10), the hole (3) having a diameter that is substantially larger than the diameter of the central portion (4a) of the covering cap (4) and substantially smaller than the diameter of the end portion (4b) of the covering cap (4) at the end for the insertion of the needle (5), a collar (11) being provided around the hole, the collar extending from the face (9) for the insertion of the covering cap.
