David Haddleton,Francois LeColley,Lei Tao,Giuseppe Mantovani,Adrian Carmichael,Adam Peter Jarvis,Andrew Gregory Steward
申请号：
US11498525
公开号：
US08436104B2
申请日:
2006.08.03
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The application provides a method of producing a comb polymer comprising the steps of:(a) Providing: (i) a plurality of monomers which are linear, branched or star-shaped, substituted or non-substituted, and have an olefinically unsaturated moiety, the olefinically unsaturated moiety being capable of undergoing addition polymerization(ii) an initiator compound the initiator compound comprising a homolytically cleavable bond.(iii) a catalyst capable of catalysing the polymerization of the monomer and(b) Causing the catalyst to catalyse, in combination with the initiator, the polymerization of a plurality of the monomers to produce the comb polymer.Catalysts and polymers obtainable by the process are also provided.Preferably, the comb polymer is capable of binding proteins and may be produced from monomers which are alkoxy polyethers, such as poly(alkyleneglycol) or polytetrahydrofuran.
