Robert Hershberg;Muralikrishna Duvvuri;Gregory Dietsch;J. Jeffry Howbert
发明人:
J. Jeffry Howbert,Muralikrishna Duvvuri,Robert Hershberg,Gregory Dietsch
申请号:
US13550192
公开号:
US09216192B2
申请日:
2012.07.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention is directed generally to stable formulations of a TLR agonist preferably a TLR7 or a TLR8 agonist, for use in the treatment of cancer, preferably solid tumors and lymphomas. Specifically, the present invention is directed to stable formulations of up to 50 mg/ml of a TLR agonist which comprise a cyclodextrin.