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Peptide scaffold design
专利权人:
BIONOR IMMUNO AS
发明人:
LANGE EINAR TØNNES,GRØNVOLD MAJA SOMMERFELT,HOLMBERG JENS OLOF,SØRENSEN BIRGER
申请号:
NZ61117611
公开号:
NZ611176A
申请日:
2011.12.02
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed is an isolated cell-penetrating peptide comprising the following structure X1- X2- X3- X4- X5 (formula I), wherein X1 and X3 independently define a linear sequence of any 2, or 3 arginines; X2 and X4 independantly define a linear sequence of 8-15 amino acids from same antigen of HCV, CMV, HPV, or Influenza or a variant sequence thereof sharing at least 70% sequence identity to the native sequence; said sequence X4 being different from X2; and wherein X5 is an optional arginine.
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