An elongated flexible sleeve over the endoscope accessory shaft and secured to the endoscope accessory shaft at the proximal portion protects the shaft of the endoscope accessory from touching the external objects before the endoscope accessory shaft is inserted into endoscope biopsy port and after the endoscope accessory shaft is withdrawn from the endoscope biopsy port. In use, the endoscope accessory cover stays outside of the endoscope biopsy port at all times. The sleeve may be supplied with a handle with a coupling piece at the distal end for removably connect to the endoscope biopsy port cap. The distal end portion of the endoscope accessory cover also may be supplied with an absorbent liner to wipe off secretions during endoscope accessory withdrawal.
