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DIARYLPYRIDAZINONE DERIVATIVES PREPARATION THEREOF AND USE THEREOF FOR THE TREATMENT OF HUMANS
专利权人:
发明人:
DUPONT PASSELAIGUE ELISABETH,LE ROY ISABELLE,MIALHE SAMUEL,PIGNIER CHRISTOPHE
申请号:
IN4966/DELNP/2013
公开号:
IN2013DN04966A
申请日:
2013.06.04
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
The present invention relates to diarylpyridazinone derivatives that block the potassium Kv channels (specifically the Kv1.5 Kv4.3 and Kv11.1 channels) and to the use thereof for the treatment of humans. Said compounds have the general formula (I) where R and R are simultaneously or independently one or more groupings such as: halogen such as F Br Cl a straight or branched C Calkyl hydroxy a straight or branched C Calkoxy arylsulfonamido in which the aryl is optionally replaced with a straight or branched C Calkyl or nitrile as well as the various enantiomers and the mixtures thereof in any proportion and the pharmaceutically acceptable salts thereof.
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