Hao YAN;Dawei JIANG;Zhilei GE;Hyung-Jun IM;Christopher ENGLAND;Peng HUANG;Chunhai FAN;Weibo CAI
发明人:
Hao YAN,Dawei JIANG,Zhilei GE,Hyung-Jun IM,Christopher ENGLAND,Peng HUANG,Chunhai FAN,Weibo CAI
申请号:
US16492099
公开号:
US20200101101A1
申请日:
2018.03.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are methods of treating acute kidney injury. The A method can include administering a sufficient amount of a DNA origami nanostructure to a subject afflicted with AKI to increase an excretory function of said subject. In some examples, the DNA origami nanostructure includes a scaffold strand and a plurality of staple strands, in which the scaffold strand comprises a M1 3 viral genome having a length of 7249 base pairs; and each staple strand of the plurality of staple strands has a length of about 20 to 60 base pairs.