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Improved glucocorticoid therapy
专利权人:
DUOCORT PHARMA AB
发明人:
LENNERNAS, HANS,JOHNSSON, JORGEN,HEDNER, THOMAS,JOHANNSSON, GUDMUNDUR,SKRTIC, STANKO
申请号:
NZ60201010
公开号:
NZ602010A
申请日:
2010.04.07
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
602010 Disclosed herein is a manufacturing process when used to produce a composition comprising: 1.5 wt % to 6.5 wtl% of one or more glucocorticoids 15 wt% to 25 wt % polymer or binder 30 wt% to 40 wt% filler 0.1 wt% to 0.5 wt% glidant 0.1 wt% to 0.5 wt% lubricant 1 wt% to 5 wt% of film coating system and 25 wt% to 40 wt% solvent, wherein the percentages are given as % of the total weight of all ingredients used in the manufacture of the composition and wherein the manufacturing process comprises a step where the solvent is wholly or partially evaporated, and wherein the ratio between a first immediate release part and a second extended release part in the composition is in a range of 20-30% of the glucocorticoid for the coating (first part) of the total amount of glucocorticoid and 70-80% of the core (second part) of the total amount of glucocorticoid.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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