Method and culture medium for preparing mammalian ovum or embryo in which zona pellucida has been thinned or eliminated, and method for fertilization using mammalian ovum prepared by same method
NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY
发明人:
Nakagata Naomi,Takeo Toru
申请号：
US201615239428
公开号：
US9994868(B2)
申请日:
2016.08.17
申请国别(地区):
美国
年份:
2018
代理人:
Hunton Andrews Kurth LLP
摘要：
Provided are a method for preparing a mammalian ovum or embryo in which zona pellucida has been thinned or eliminated, and a method for fertilization using the mammalian ovum prepared by the aforementioned method. The resulting mammalian ovum or embryo is capable of realizing an improved fertilization rate and development rate when used for in vitro fertilization, transplantation of a fertilized ovum, or for preparation of an embryo in the early stages of development used in the production of a genetically modified animal.
