Siegel, Dustin Scott,Karki, Kapil Kumar,Schrier, Adam James,Jansa, Petr,Mackman, Richard,Aciro, Caroline,Steadman, Victoria Alexandra,Pettit, Simon Neil,Poullennec, Karine G.,Lazarides, Linos,Dean, Da
申请号：
NZ72461613
公开号：
NZ724616A
申请日:
2013.06.07
申请国别(地区):
NZ
年份:
2018
代理人:
摘要：
Provided are compounds of Formula I and pharmaceutically acceptable salts and esters thereof, wherein A1 is (C2-C5)alkylene, (C2-C5)alkynylene, -O-(C2-C4)alkylene, -O-(C2 C4)alkenylene, arylene, aryl(C1-C2)alkylene, heterocycloalkylene, pyrazolylene, pyridylene or heterocycloalkyl(C1 C2)alkylene, wherein a sp3 carbon atom of A1 is optionally substituted with one or more (C1-C4)alkyl A2 is arylene or heteroarylene, wherein A2 is optionally substituted with halo. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.
