These compounds possess anti-inflammatory activity.Claim 1: a compound of formula (1), wherein: R1 represents optionally substituted aryl or heteroaryl Groups by one or more elected irrespective of halogen, alkyl haloalquilo C1 C1 - 8 - 8 - 8 - rent, R2O C0, R2S C0 - 8 - alkyl, cyano, Nitro, nr2r4 -, - nr2so2r3 Sor3 so2r3, -, -, - or - so2nr2r4 conr2r4； R2 represents Hydrogen,Alkyl aryl alkyl - 8 C1 or C0 - 8 (where the aryl Group can be optionally substituted by one or more selected from alkyl groups C1 - 8 - 8 haloalquilo C1, halogen, Nitro, cyano, r5o alkyl, alkyl R5S C0 - 8 - 8 - nr5r6, C0, - nr5cor3, - cor5 or - coor5)； R3 represents alkyl group or C1 - 8 h Aloalquilo C1 - 8 alkyl； R4 represents Hydrogen, C1 - 8Aryl alkyl C1 - 8 (where the aryl Group can be optionally substituted by one or more selected from alkyl groups C1 - 8 - 8 haloalquilo C1, halogen, Nitro, cyano, C0, r5o alkyl alkyl R5S C0 - 8, - 8, - nr5r6 nr5cor3 cor5, -, -, - coor5 cor6) - or - coor6 R5 represents Hydrogen；C1 - 8 alkyl or benzyl； R6 represents alkyl or haloalquilo C1 C1 - 8 - 8； aryl and heteroaryl represents phenyl or naphthyl represents； pyridine, pyrazine, pyrimidine or pyridazine hydrochloride, which can be optionally FUSED to a benzene Ring； and a represents Tert Butyl.Estos compuestos poseen actividad antiinflamatoria.Reivindicación 1: Un compuesto de fórmula (1), caracterizado porque: R1 representa arilo o heteroarilo opcionalmente sustituido por uno o más grupos elegidos independientemente de entre halógeno, alquilo C1-8, haloalquilo C1-8, R2O-alquilo C0-8, R2S-alquilo C0-8, ciano, nitro, -NR2R4, -NR2SO2R3, -SOR3, -SO2R3, -SO2NR2R4 o -CONR2R4； R2 representa hidrógeno, alquilo C1-8 o aril-alquilo C0-8 (donde el grupo arilo puede estar opcionalmente sustituido por uno o más grupos elegidos de entre alquilo C1-8, halógeno, haloalquilo C1-8, ciano, nitro, R5O-alquilo C0-8, R5S-alquilo C0-8, -NR5R6, -NR5COR3, -COR5 o -COOR5)； R3 representa un grupo alquilo C1-8 o haloalquilo C1-8；
