To provide a herbicidal composition which is highly safe for cultivated plants, and can exhibit a synergistic effect of its active ingredients to effectively control a variety of weeds and the like at a lower dosage, a method of use, and a method for controlling weeds. Provided are a herbicidal composition characterized by containing, as an active ingredient, one or more compounds selected from the group consisting of pyraflufen-ethyl, and a very long chain fatty acid synthesis inhibitor or a photosynthesis inhibitor, a method of using the same, and a method for controlling weeds.本發明係提供一種除草劑組成物、使用方法及雜草防治方法，該除草劑組成物對栽培植物之安全性高且可發揮有效成分之相乘效果而以更低藥量來有效地防治更多種類之雜草等。本發明的解決手段為一種除草劑組成物、及其使用方法以及雜草防治方法，該除草劑組成物之特徵為含有乙基派芬草、及選自包含超長鏈脂肪酸合成抑制劑或光合成抑制劑之群組的1種或2種以上之化合物作為有效成分。
