Ahmad, Saleem,Tino, Joseph A.,Macor, John E.,Tebben, Andrew J.,Gong, Hua,Liu, Qingjie,Batt, Douglas G.,Ngu, Khehyong,Watterson, Scott Hunter,Guo, Weiwei,Beaudoin Bertrand, Myra
申请号：
AU2019283921
公开号：
AU2019283921A1
申请日:
2019.12.19
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2019283921A120200116.pdf#####INDOLE CARBOXAMIDE COMPOUNDS ABSTRACT Disclosed are compounds of Formula (I): o NH 2 H N R 1 5 R2 A (I) or a salt thereof, wherein: X is CR4 or N； R1 , R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a 10 variety of therapeutic areas, such as autoimmune diseases and vascular disease. -311-
