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EXTRACTS OF SHARK CARTILAGE HAVING ANTI-COLLAGENOLYTIC, ANTI-INFLAMMATORY, ANTI-ANGIOGENIC AND ANTI-TUMORAL ACTIVITIES AND COMPOSITIONS THEREOF
专利权人:
发明人:
DUPONT ERIC,BRAZEAU PAUL,JUNEAU CHRISTINA,MAES DANIEL H,MARENUS KENNETH
申请号:
IN251/CAL/2002
公开号:
IN2002CA00251A
申请日:
2002.05.01
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
A cartilage extract obtained from shark and produced by a method comprising the steps of: a) homogenizing the cartilage in an aqueous solution a conditions compatible with the preservation or the integrity of said biologically active components until the cartilage is reduced to particles whose size is lower than or equal to about 500 µm, resulting in a mixture or particles and of a crude liquid extract having said biologically active components b) separating the particles from the crude liquid extract c) separating the crude liquid extract of b) so as to obtain a final liquid extract containing cartilage molecules having a molecular weight lower than or equal to about 500 Kilodaltons (KDa) and d) concentrating said final liquid extract, whereby at least a portion of molecules having a molecular weight lower than 100 Daltons is removed.
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