LAMBERT, ROBERT L.,兰伯特 罗伯特L,蘭伯特 羅伯特L,兰伯特 罗伯特Ｌ,蘭伯特 羅伯特Ｌ
申请号：
TW102138534
公开号：
TWI632923B
申请日:
2013.10.24
申请国别(地区):
TW
年份:
2018
代理人:
摘要：
Compositions for the transdermal delivery of amphetamine in a flexible, finite form are described. The compositions comprise a polymer matrix that includes amphetamine or a pharmaceutically acceptable salt or prodrug thereof and a backing layer comprising a polyurethane film layer and a polyester film layer, with a polyurethane adhesive disposed therebetween. Related methods also are described. Also described are compositions that exhibit a short onset period and a long duration of therapeutic effect.本發明闡述用於經皮傳遞呈撓性有限形式之安非他命(amphetamine)之組合物。該等組合物包含包括安非他命或其醫藥上可接受之鹽或前藥之聚合物基質及包含聚胺基甲酸酯膜層及聚酯膜層之背襯層,且該等層之間佈置有聚胺基甲酸酯黏著劑。本發明亦闡述相關方法。本發明亦闡述呈現起效時間短及療效持續時間長之組合物。
