The Trustees of Columbia University;Children's Hospital Medical Center;Childrens Hospital Medical Center
发明人:
Devarajan, Prasad,Mori, Kiyoshi,Barasch, Jonathan M.
申请号：
AU2005240190
公开号：
AU2005240190C1
申请日:
2005.05.06
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
Use of neutrophil gelatinase-associated lipocalin (NGAL) as a therapeuticand in a method of treating, reducing, or ameliorating an injury selected froman ischemic injury, an ischemic-reperfusion injury, and a toxin-induced injury,to an organ in a patient. The invention includes administering to the patientNGAL in an amount effective to treat, reduce or ameliorate ischemic, ischemic-reperfusion,or toxin-induced injury to the organ, such as the kidney. A siderophore can beco-administered with the NGAL. The invention also relates to administeringa sideophore to enhance a response to secretion of NGAL following an ischemicor toxin-induced injury to an organ in a patient.
